In the first stage of this research, interviews are conducted with five universities, the association of Dutch universities and the Dutch association of scientific research. The result of this first phase is a clear definition when an university is successful in knowledge valorisation and an overview of the factors that might influence this success. In the second phase the significance of these factors is investigated with a survey among 125 randomly selected universities in Europe, the USA and Australia. A regression analysis will be used to examine the relation between the critical success factors and the success of knowledge valorisation. To compare the success of university knowledge valorisation between the three continents, T-tests will be used.