GBS PCR | QuestionPro

If a rapid/sensitive GBS screen were available would it alter your care?

Yes

Maybe in some cases

How rapid would the test results need to be available to be clinically useful?

2 hour turnaround

4 hour turnaround

12 hour turnaround

A. The CDC states in footnotes for Figures 5 and 6 that, "A negative GBS screen is considered valid for five weeks." This is true for both Preterm Labor (PTL) and Preterm Premature Rupture of Membranes (P-PROM).

A1. Patient presents at 25 weeks in preterm labor and has a negative GBS screen. Labor is stopped but she presents at 28 weeks in active labor with expected delivery >4 hours.

I would not provide Intrapartum Antibiotic Prophylaxis (IAP) as the culture was negatvie less than five weeks prior.

I would provide IAP as this is a preterm infant.

A2. For the same patient in quesiton A1, if there is a rapid/sensitive screening test for GBS with a quick turnaround time

I would not obtain this GBS screen as it would not alter my decision for antibiotics/no antibiotics as answered above.

I would obtain rapid GBS screen and initiate IAP with positive result.

I would initiate IAP but discontinue if rapid GBS screen was negative.

B. The CDC states in footnotes for Figures 5 and 6 that, "A negative GBS screen is considered valid for five weeks." This is true for both Preterm Labor (PTL) and Preterm Premature Rupture of Membranes (P-PROM).

B1. Patient presents at 25 weeks with P-PROM, receives a full dose of latency antibiotics and has a negative GBS screen. Labor is stopped, but she presents at 28 weeks in active labor with expected delivery >4 hours.

I would not provide IAP as the culture was negative less than five weeks prior.

I would provide IAP as this is a preterm infant.

B2. For the same patient in question B1, if there is a rapid/sensitive screening test for GBS with a quick turnaround time

I would not obtain this GBS screen as I would not alter my decision for antibiotics/no antibiotics as answered above.

I would obtain rapid GBS screen and initiate IAP with positive result.

I would initiate IAP but discontinue if rapid GBS screen was negative.

C1. A patient presents at 25 weeks with preterm labor which was stopped. She has a positive GBS screen. She now presents at 28 weeks in active labor with delivery expected >4 hours. If there is a rapid/sensitive screening test for GBS with a quick turnaround time

I would not obtain this GBS screen as I would provide IAP for the prior positive screen.

I would obtain rapid GBS screen and initiate IAP with positive result.

I would initiate IAP but discontinue if rapid GBS screen was negative.

C2. A patient presents at 25 weeks with P-PROM, receives a full dose of latency antibiotics and has a positive GBS screen. Labor is stopped but she presents at 28 weeks in active labor with expected delivery >4 hours. If there is a rapid/sensitive screening test for GBS with a quick turnaround time

I would not obtain this GBS screen as I would provide IAP for the prior positive screen.

I would obtain rapid screen and initiate IAP with positive result.

I would initiate IAP but discontinue if rapid GBS screen was negative.